Meeting Agenda

The International Conference on Polyphenols will take place at Memorial Union on the University of Wisconsin – Madison campus.


*Tentative Agenda – Details Subject to Change*


Monday, July 16, 2018


8:00 AM – 5:00 PM Registration Annex
8:30 AM – 8:40 AM Opening Ceremony Shannon Hall
8:40 AM – 8:55 AM Ragai Ibrahim Tribute Lecture

Denis Barron

Shannon Hall
8:55 AM – 9:45 AM Opening Lecture

Navindra Seeram, USA

Shannon Hall


Session Topic 1

9:45 AM

Chemical and Physical-Chemistry Shannon Hall
9:45 AM Plenary: Total Synthesis of Complex Natural Flavonoids and Isoflavonoids Keisuke Suzuki


10:30 AM Theoretical Study of the inhibition of p90 Ribosomal S6 Kinase by Flavonoid Compounds Serge Antonczak


10:45 AM Extending the blue color stabilization of anthocyanin derivatives Luis Cruz


11:00 AM Coffee Break Lobby
11:30 AM Red cabbage anthocyanins: water addition, acid – base equilibria and chemical stability in acidic to mildly alkaline conditions Oliver Dangles


11:45 AM Using density functional theory (DFT) to understand the loss of red color intensity of anthocyanin esters obtained by chemical lipophilization of Delphinidin 3-O-Sambubioside Ana Selene Marquez


12:00 PM Advances on iron gall inks: revealing the complex polyphenol systems used to write the medieval book Maria J. Melo


12:15 PM – 2:00 PM Lunch Tripp Commons
Session Topic 1 Cont’d

2:00 PM

Chemical and Physical-Chemistry Shannon Hall
2:00 PM Lignin and lignin-derivatives as a tool to stabilize/modulate the colour of anthocyanins and anthocyanin-derived pigments in aqueous systems Joana Oliveira


2:15 PM Towards Molecular Machines Based on Polyphenols A. Jorge Parola


2:30 PM Polyphenols interaction with salivary proteins and with bitter taste receptors Susana Soares


2:45 PM Polyphenols in White and Red Poinsettia Bracts Carmen Stefanini


3:00 PM Membrane Crossing by Polyphenols Patrick Trouillas


3:15 PM Coffee Break Lobby
3:45 PM Physico-Chemical Characterization of Red Wine Astringency Aude Watrelot


4:00 PM Non-Enzymatic Oxidation of a Pentagalloylglucose Analogue into Members of the Ellagitannin Family Hidetoshi Yamada


4:15 PM Plenary: Achieving Complexity at the Bottom through the Flavylium Cation Based Multistate Fernando Pina


5:00 PM – 7:00 PM Poster Session Reception Great Hall


Tuesday, July 17, 2018


8:00 AM – 5:00 PM Registration Annex
Session Topic 2

9:00 AM

Biosynthesis, Genetics and Metabolic Engineering Shannon Hall
9:00 AM Plenary: Dissecting the Diversification of Plant Polyphenols David Gang


9:45 AM A Metabolic Bottleneck in the Phenylpropanoid Pathway Mediates Phloridzin Accumulation in Apple (Malus × domestica) Andrew Dare


10:00 AM Purification and initial characterization of a dehydrogenase from apple (Malus × domestica) that is involved in phloridzin biosynthesis Heidi Halbwirth


10:15 AM Reinvestigating Substrate Specificty of Dihydroflavonol 4-Reductase of Petunia × Hybrida Daria Nitarska


10:30 AM Coffee Break Lobby
11:00 AM ‘Designing’ Biomass Lignins for the Biorefinery John Ralph


11:15 AM A Candidate Gene of Chalcone Reductase in Butein Biosynthesis in Dahlia Haruka Yamada


11:30 AM Plenary: Complex regulation of proanthocyanidin biosynthesis in plants by R2R3 MYB activators and repressors C. Peter Constabel


12:15 PM – 2:00 PM Lunch Tripp Commons
2:00 PM Award Talk Shannon Hall
Session Topic 3

2:45 PM

Tannin Conference Shannon Hall
2:45 PM Plenary: A Little Bit of Glucose and a Lot of Gallic Acid, the Main Ingredients for the Total Synthesis of the Ellagitannin Vescalin and the Gallotannin Tannic Acid Stéphane Quideau


3:15 PM Are Polysaccharides Important to Modulate Protein/Tannin Interactions? Elsa Brandão


3:30 PM Coffee Break Lobby
4:00 PM Depolymerized Condensed Tannins as Biobased Aromatic Building Blocks Helene Fulcrand


4:15 PM Direct and Sequential Analysis of Condensed Tannins by an Optimized HCl-Butanol-Acetone-Iron Assay John Grabber


4:30 PM Effects of Copper (II) on Epigallocatechin Gallate-Serum Albumin Interactions Ann Hagerman


4:45 PM Reversible Self-Aggregation of Oxidized Tannins in Model Solutions Ivana Horvat


5:00 PM – 7:00 PM Poster Session Reception Great Hall


Wednesday, July 18, 2018


8:00 AM – 5:00 PM Registration Annex
Session Topic 3 Cont’d

9:00 AM

Tannin Conference Shannon Hall
9:00  AM Plenary: Application-Specifc Analytical Chemistry: Matching Proanthocyanidin Use with Appropriate Analytical Method James Kennedy


9:45 AM Conformation and Aggregation of Human Serum Albumin in the Presence of EGCg and Palmitic Acid Xiaowei Sun


10:00 AM Anthelmintic Proanthocyanidin Oligomers and Polymers and their Modification by Oxidation in Alkaline Conditions Iqbal Bin Imran


10:15 AM Synthesis of Crown Procyanidins Tetramer Alicia Jouin


10:30 AM Coffee Break Lobby
11:00 AM How to Produce Chemically Well-Defined Semipreparative Proanthocyanidin Fractions from Complex Mixtures of Oligomers and Polymers? Milla Leppä


11:15 AM Cranberry Proanthocyanidin-Chitosan Composite Nanoparticles as Potential Nanoantibiotics Against Extra-Intestinal Pathogenic Escherichia Coli Sergio Madrigal-Carballo


11:30 AM Stereoselectivity in Oxidative Dimerization of Catechins during Tea-fermentation Yosuke Matsuo


11:45 AM “Tannins” in Chemistry and Applied Sciences: We Need a Change in the Use of Definitions and Detection Techniques Juha-Pekka Salminen


12:00 PM Impact on Color Copigmentation of Malvidin-3-O-Monoglucoside Solutions by Supplementation with Oenological Tannins Adeline Vignault


12:15 PM Elucidating Composition and Structure of Purified Condensed Tannins: Corroboration of Wet Chemistry and Spectroscopic Data Wayne Zeller


12:30 PM – 2:00 PM Lunch Tripp Commons
Session Topic 4

2:00 PM

Human and Animal Nutrition and Health Shannon Hall
2:00 PM Plenary: The Ups and Downs of Analyzing Bioactive Proanthocyanidins Irene Mueller-Harvey


2:45 PM Molecular Insights on the Interaction and Preventive Potential of Dietary Polyphenols in Celiac Disease Ricardo Dias


3:00 PM Impact Of Raspberry Consumption On Cognition And Cerebral Microvascular Architecture Chris Gill


3:15 PM Coffee Break Lobby
3:30 PM Bread Fortification with Flavonoid-Rich Legume Microgreens and Leaves Rebecca Klopsch


3:45 PM Cranberry Proanthocyanidins Mitigate Reflux-Induced Transporter Dysregulation in Esophageal Adenocarcinoma Laura A. Kresty


4:00 PM Fisetin and its Derivatives for the Treatment of Age-Associated Neurodegenerative Diseases Pamela Maher


4:15 PM Unveiling the Molecular Mechanism of Acylated Anthocyanins Gastrointestinal Absorption Hélder Oliveira


4:30 PM Phenolipids Based on Protocatechuic Acid Alkyl Esters Trigger Disruption of Mitochondrial Membrane Potential and Caspase Activation in Macrophages David Pereira


5:00 PM – 7:00 PM Poster Session Reception Great Hall


Thursday, July 19, 2018


8:00 AM – 5:00 PM Registration Annex
Session Topic 4 Cont’d

9:00 AM

Human and Animal Nutrition and Health Shannon Hall
9:00 AM Plenary: Answering the Call of the Wild: Polyphenols in Traditional Therapeutic Practice Mary Ann Lila


9:45 AM Food Tannins as Modulators in Transepithelial Passage of Celiac Disease-Related Peptides Maria Rosa Perez-Gregorio


10:00 AM Resveratrol Attenuates the Need for Increased Oxygen and Prevents Cognitive Deficits during Hypoxia in Young, Healthy Humans Emma Wrightman


10:15 AM Modulatory Effects of Polyphenols on Type-2 Immune Function Andrew Williams


10:30 AM Coffee Break Lobby
Session Topic 5

11:00 AM

Roles in Plants and Ecosystems Shannon Hall
11:00 AM Plenary: Flavonols and the Evolvability of Land Plants Massimiliano Tattini


11:45 AM Enzymatic Oxidation of Phenolic Compounds in Plants Depends Primarily on the Mono-, di- or trihydroxysubstitution of their Phenolic Moieties Jorma Kim


12:00 PM The Interlink of UV Transmittance and Flavonoids in Okra Driven by Diurnal Changes Susanne Neugart


12:30 PM – 2:00 PM Lunch Tripp Commons
Session Topic 5 Cont’d

2:00 PM

Roles in Plants and Ecosystems Shannon Hall
2:00 PM Substrate Specificity of Polyphenol Oxidases of Apple Shed New Light on their Physiological Role Barbara Roth


2:15 PM Plant Polyphenols and their Dynamics during Leaf Development under Nutrient Limitation: A Potential Nutrient Conservation Strategy for Mangrove Plant Haichao Zhou


2:30 PM Plenary: Variation in Proanthocyanidin Expression in Populus: A Molecules to Ecosystems Perspective Rick Lindroth


3:15 PM General Assembly Meeting Shannon Hall
6:30 PM Cocktails Great Hall
7:00 PM Closing Banquet Great Hall


Friday, July 20, 2018


8:00 AM – 2:00 PM Registration Annex
Session Topic 6

9:00 AM

Applied Polyphenolics Shannon Hall
9:00 AM Plenary: Advanced Analytic Methods for the Authentication, Standardization and Efficacy Evaluation of Natural Products Chris Krueger


9:45 AM Nanotechnology as a Useful Tool for Polyphenol Research and Development Emilia Alfaro-Viquez


10:00 AM Preparative Fractionation of 5’-O-Caffeoylquinic Acid Oxidation Products using Centrifugal Partition Chromatography and their Characterization by Mass Spectrometry Claudia Mariana Castillo Fraire


10:15 AM Towards Eco-Designed Phenolic Bioproducts without Hormonal Side Effects Helene Fulcrand


10:30 AM Coffee Break Lobby
11:00 AM Does UV-Light Modify the Antimicrobial and Antioxidant Activity of the Bark Extracts? Tuula Jyske


11:15 AM Changes in the Flavonoid Pathway during the Last Four Weeks of Fruit Ripening in an Apple Cultivar Showing Bicolored Fruit Flesh Martina Kolarek


11:30 AM Evaluation of the Presence of Antioxidant and Antimicrobial Activity of Condensed Tannins Present in the Fruit Exocarp of Seven Varieties of Rambutan (Nephelium lappaceum L.) Gerardo Rodríguez Rodríguez


11:45 AM Determination of Polyphenol Mangiferin by LC-MS/MS in Rat and its Comparative Pharmacokinetic Study of a Single Compound, a Single Botanic Extract and Multiple Botanic Complex Tung-Hu Tsai


12:00 PM Plenary: Lignin Monomers from the Flavonoid and Stilbene Biosynthetic Pathways José Carlos del Rio


12:45 PM Closing Remarks Shannon Hall