*Agenda subject to change*
| September 30th | Tuesday | |
| 2:00pm | Registration Open | Annex Room |
| 6:00pm | Welcome Reception | |
| 7:00pm | Keynote Address
Dr. Dennis Burton Nonhuman primates: invaluable in the quest for an antibody-based HIV vaccine |
Tripp Commons |
| October 1st | Wednesday | |
| 7:00am-5:00pm | Registration Open | Annex Room |
| 7:00am | Poster Session Setup | Tripp Commons |
| 7:15am | Continental Breakfast | Reception Room |
| 8:00am | Welcome to the Conference | Great Hall |
| 8:15am | Named Travel Award Presentations | Great Hall |
| 8:30am | Immune Dynamics: Vaccines and Host Responses
Chair: David Evans, PhD |
Great Hall |
| 8:30am | Adeno-Associated Virus Delivery of Neutralizing Antibodies Affords Durable Protection against Mucosal Challenge with SIVmac239 | David Evans |
| 9:00am | Modulation of Rhesus Macaque Killer Cell Ig-Like Receptor-MHC I Interactions by Simian Immunodeficiency Virus Peptides | Kjell Sandstrom |
| 9:15am | Cocaine-dependent modulation of host invariant natural killer cells during simian immunodeficiency virus infection in Rhesus Macaques | Gokul Raj Kathamuthu |
| 9:30am | Follicular Homing CD8 T cells/NK cells induced by IL-15/IL-15Ra therapy mediate control of viral rebound in SIV-infected macaques | Sakthivel Govindaraj |
| 9:45am | Break
Refreshments: Reception Room Sponsors/Exhibitor Tables: Great Hall Foyer Poster Viewing: Tripp Commons |
Various |
| 10:15am | Immune Dynamics: Vaccines and Host Responses Continued
Chair: David Evans, PhD |
Great Hall |
| 10:15am | Primate resident memory T cells activate humoral and stromal immunity | Vineet Joag |
| 10:30am | HIV envelope variable region 1 (V1) abrogates vaccine efficacy by recruiting plasmacytoid dendric cells and counteracting the ATP/ CD73 axis | Genoveffa Franchini |
| 10:45am | HIV vaccine candidate mucosal immunity augmented by V1-deleted gp120 formulated in Alum and ALFQ adjuvant | Massimiliano Bissa |
| 11:00am | Elicitation of antibody responses targeting HIV-1 broadly neutralizing epitopes by multiple founder variant-type Env vaccines in rabbits and macaques | Thujitha Thuraisamy |
| 11:15am | Impaired antibody and alveolar macrophage responses during SARS-CoV-2 rechallenge in SIV+ rhesus macaques | Megan O’Connor |
| 11:30am | A Single Dose of Neutralizing Antibody Partially Protects Owl Monkeys (Aotus nancymaae | Sara Sawyer |
| 11:30am | Lunch on own | |
| 11:30am | Poster Viewing | Tripp Commons |
| 11:30am | Sponsor/Exhibitor Tables Open | Great Hall Foyer |
| 11:30am | Trainee Networking Social
(Students, Postdocs & Residents Only) |
Old Madison |
| 1:30pm | Reservoirs and Remission: Viral Sanctuaries & Clearance Strategies
Chair: Ann Chahroudi, MD |
Great Hall |
| 1:30pm | Non NAM, no cry: discoveries in viral persistence and cure using nonhuman primates | Ann Chahroudi |
| 2:00pm | Defining the dynamics of SIV infection and the viral reservoir from early ART initiation to Rebound using PET/CT analysis and a multi-scale imaging approach | Yanique Thomas |
| 2:15pm | Characterizing Viral Reservoir Dynamics in Infant Macaques Using Multiplex ISH/IHC Following ART and AAV9-Mediated Monoclonal Antibody Therapy | Rachael Wolter |
| 2:30pm | Establishing Defined SIV Reservoirs to Determine the Relationship Between Reservoir Size and Rebound Time | Ally McCullen |
| 2:45pm | Break
Refreshments: Reception Room Sponsors/Exhibitor Tables: Great Hall Foyer Poster Viewing: Tripp Commons |
Various |
| 3:15pm | Reservoirs and Remission: Viral Sanctuaries & Clearance Strategies Continued
Chair: Ann Chahroudi, MD |
Great Hall |
| 3:15pm | Single-cell chimeric virus-host transcripts reveal SIV integration sites and atypical gene expression in SIV RNA+ CD4 T cells from infected macaques | Diane Bolton |
| 3:30pm | SIV vRNA+ CD4 T cells predominate in lymph nodes and intestinal mucosa after antiretroviral drug therapy interruption | Pamela Skinner |
| 3:45pm | IL-21 and IL-15 Differentially Modulate Viral Persistence and Neuroimmune Signatures in SIV-Infected Brain | Sabrina Tan |
| 4:00pm | Tankyrase inhibition reverses HIV/SIV latency and limits rhesus macaque CD4+ T cell proliferation | Riri Hamid |
| 4:15pm | Generation of SIV Resistant and Engraftable Hematopoietic Stem and Progenitor Cells from Nonhuman Primate Induced Pluripotent Stem Cells | Samuel Dettle |
| 4:30pm | Pitch Your Poster! 1-minute rapid talks | |
| 6:00pm | Poster Reception | Tripp Commons |
| October 2nd | Thursday | |
| 7:00am-5:00pm | Registration Open | Annex Room |
| 7:15am | Poster Viewing | Tripp Commons |
| 7:15am | Sponsor/Exhibitor Tables Open | Great Hall Foyer |
| 7:30am | Continental Breakfast | Reception Room |
| 8:30am | Delivery Innovations: Vector Systems & Targeted Immunotherapies
Chair: Jonah Sacha, PhD |
Great Hall |
| 8:30am | AAV delivery of antibody-mediated CCR5 blockade for HIV treatment | Jonah Sacha |
| 9:00am | AAV-Vectored Delivery of eCD4-Ig and 10-1074 Enable Durable, ART-Free Virologic Control in SHIV-Infected Rhesus Macaques Beyond Infancy | Patricia Hahn |
| 9:15am | Interventions in SHIV-Infected Macaques Treated with AAV-Delivered Antibodies | Jose M. Martinez-Navio |
| 9:30am | AAV-delivery of anti-CCR5 blocking antibody for pediatric HIV prevention | Gabriela Webb |
| 9:45am | Break
Refreshments: Reception Room Sponsors/Exhibitor Tables: Great Hall Foyer Poster Viewing: Tripp Commons |
Various |
| 10:15am | Delivery Innovations: Vector Systems & Targeted Immunotherapies Continued
Chair: Jonah Sacha, PhD |
Great Hall |
| 10:15am | Ultra-high concentration microparticle formulation of LS-variant anti-CCR5 monoclonal antibody provides protection against intrarectal SHIV acquisition in rhesus macaques | Helen Wu |
| 10:30am | Defining the Window of Opportunity for HIV Peri-exposure Immunoprophylaxis with Bispecific Monoclonal Antibody 10E8.4/iMab against High-dose Intravenous SHIV Challenge in Rhesus Macaques | Caroline Subra |
| 10:45am | A model of minor antigen adoptive T cell immunotherapy in Mauritian Cynomolgus Macaques | Octavia Hogaboam |
| 11:00am | CAR/CCR9 T cell immunotherapy shows promise in localization of SIV-specific CAR T cells to the gastrointestinal tract of rhesus macaques | Mary Pampusch |
| 11:15am | Depleting the Latent HIV Reservoir with Anti-CD4 CAR T-Cells | Carly Starke |
| 11:30am | Lunch on own | |
| 11:30am | Poster Viewing | Tripp Commons |
| 11:30am | Sponsor/Exhibitor Tables Open | Great Hall Foyer |
| 1:15pm | Journal of Medical Primatology | |
| 1:30pm | Beyond HIV: Co-Infections & Emerging Pathogens
Chair: Sallie Permar, MD |
Great Hall |
| 1:30pm | A Vaccine for Congenital CMV: How Close Are We? | Sallie Permar |
| 2:00pm | Rhesus Macaques with Plasmodium fragile Malaria in Pregnancy Have Smaller Fetuses but Minimal Alterations in Decidual Vascularization | Sallie Fell |
| 2:15pm | Effects of Plasmodium fragile Malaria in Pregnancy on Maternal Blood-Brain Barrier Integrity and Microglia Morphology in the Hippocampus | James Prusak Jr. |
| 2:30pm | Variable immune responses at time of fetal demise in a pregnant rhesus macaque model of MPXV Clade IIb infection | Savannah Lutz |
| 2:45pm | Development of T-cell-based immunotherapy against chronic Hepatitis B infection | Sofiya Yusova |
| 3:00pm | Break
Refreshments: Reception Room Sponsors/Exhibitor Tables: Great Hall Foyer Poster Viewing: Tripp Commons |
Various |
| 3:30pm | Beyond HIV: Co-Infections & Emerging Pathogens Continued
Chair: Sallie Permar, MD |
Great Hall |
| 3:30pm | Broadly neutralizing anti-alphavirus antibodies protect against Eastern Equine Encephalitis in a nonhuman primate model of aerosol exposure | Brandon Beddingfield |
| 3:45pm | Characterization of Aerosolized Nipah Virus Bangladesh (NiV-B) Infection in African Green Monkeys for Use Under the FDA Animal Rule | Yenny Goez-Gazi |
| 4:00pm | Prevention of tuberculosis by safe, next-generation, human-ready, stress-response deficient live Mtb candidate vaccines – studies in immunocompetent and SIV-co-infected macaques | Deepak Kaushal |
| 4:15pm | Efficacy and Safety of AI-enabled PRS Regimen VI (Clofazimine, Bedaquiline and Pyrazinamide) as Ultra-Short Course Therapy of LTBI in Non-Human Primates in a setting mimicking HIV co-infection | Venkata Siva Reddy Devireddy |
| 4:30pm | Early immune dysregulation in the airways of Mtb/SIV co-infected rhesus macaques despite cART administration | Shashi Prakash Singh |
| 6:00pm | Banquet Dinner | Edgewater Hotel |
| October 3rd | Friday | |
| 7:00am-12:30pm | Registration Open | Annex Room |
| 7:15am | Poster Viewing | Tripp Commons |
| 7:15am | Sponsor/Exhibitor Tables Open | Great Hall Foyer |
| 7:30am | Continental Breakfast | Reception Room |
| 8:30am | Advances: NHP Research Tools & Resources
Chair: Ben Bimber, PhD |
Great Hall |
| 8:30am | Big Data for Small Studies: Advances in NHP Omics Technologies and Resources | Ben Bimber |
| 9:00am | A Broad Survey and Functional Analysis of Immunoglobulin Loci Variation in Rhesus Macaques | Ayelet Peres |
| 9:15am | Cataloguing extensive population-level diversity in the germline immunoglobulin (IG) loci of rhesus macaque colonies across the USA | Swati Saha |
| 9:30am | Viral reservoirs in the owl monkey (Aotus nancymaae) model of HIV-1 infection | Gregory Wilkerson |
| 9:45am | Break
Refreshments: Reception Room Sponsors/Exhibitor Tables: Great Hall Foyer Poster Viewing: Tripp Commons |
Various |
| 10:15am | Advances: NHP Research Tools & Resources Continued
Chair: Ben Bimber, PhD |
Great Hall |
| 10:15am | Establishment of a Persistent HIV-1mt Infection Model in Cynomolgus Macaques Characterized by Viral Evolution and CD4⁺ T Cell Depletion | Akatsuki Saito |
| 10:30am | Immune Cell Depletions in Pregnant Macaques: Advancing Model Characterization for Maternal-Fetal Infections | Matilda Moström |
| 10:45am | Personalized libraries of SIV-Specific TCR sequences enable precise characterization of vaccine-elicited cellular immunity ex vivo and in vivo | Morgan Chaunzwa |
| 11:00am | Isolation of KIR-specific monoclonal antibodies for functional studies in rhesus macaques | Linc Reincke |
| 11:15am | Development of Oropouche virus rhesus macaque infection model | Daniel Streblow |
| 11:30am | Closing Remarks & Preview of 2026 Symposium in San Antonio, Hosted by the Southwest NPRC | Great Hall |
| 11:45am | Lunch on own | |
| 12:00pm | Remove Posters | |
| 12:00pm | Remove Sponsor/Exhibitor Tables |