2025 Schedule
All events will take place in the Memorial Union on the University of Wisconsin-Madison campus.
July 14 |
Monday |
|
12:00 PM – 7:00 PM |
Registration |
Annex Room |
5:00 PM – 7:00 PM |
Opening Reception |
Tripp Commons |
7:00 PM – 8:00 PM |
Oral Session 1: Viral Immunology Session Co-Chairs: Diana Pastrana & Wei Wang |
Shannon Hall |
7:00 PM |
WEE1 Inhibition Remodels the Tumor Microenvironment to Promote Antitumor Immunity against HPV+ Head and Neck Cancer |
Ying Liu |
7:15 PM |
The Role of the Early Region Genes in Adenovirus 7 and 14 Host Immune Evasion |
Ian McNicol |
7:30 PM |
Mechanisms of Post-Attachment Neutralization of HPV16 by Antibodies Derived from Gardasil-Vaccinated Women |
Patricia Day |
7:45 PM |
The Magnitude and Durability of Neutralizing Antibody Titers to the 9-Valent Human Papillomavirus Vaccine do not Depend on DNA Sensing Pathways |
Erin Scherer |
8:00 PM |
Immune Control and Immune Evasion Amongst HPV Infections of the Cervix |
Amy Davies |
8:10 PM |
Refreshment Break |
Shannon Hall Lobby |
8:30 PM – 9:30 PM |
Oral Session 1 Continued: Viral Immunology Session Co-Chairs: Diana Pastrana & Wei Wang |
Shannon Hall |
8:30 PM |
HPVs use Caspase Activity to Suppress Expression of Endogenous Retroviruses that Trigger an Innate Immune Response |
Cary Moody |
8:45 PM |
How to Make and Share Vaccine-Style Beer |
Safoura Soleymani |
9:00 PM |
Signaling Saboteur: Human Papillomavirus E7 Disarms IL-18 Inflammatory Signaling in Head and Neck Cancer |
Andris Evans |
9:15 PM |
Engineering Targeted Degraders of the HPV Oncoprotein E6 to Treat HPV-Positive Cancers |
Jennifer Binning |
July 15 |
Tuesday Morning |
|
7:30 AM – 5:00 PM |
Registration |
Annex Room |
8:30 AM – 10:00 AM |
Oral Session 2: Virus-Host Interactions I Session Co-Chairs: Paola Blanchette & James Romero-Masters |
Shannon Hall |
8:30 AM |
Changes to Cellular RNA Binding Proteins During Adenovirus Infection |
Matthew Weitzman |
8:45 AM |
An HPV16 E2-TOPBP1 Complex Activates the DNA Damage Response during the Viral Life Cycle |
Apurva Tadimari Prabhakar |
9:00 AM |
HPV18 Modulates Alternative Splicing through PRMT1-Dependent m6A Methylation of Viral mRNA |
Kelly King |
9:15 AM |
HIV- 1 Protease Inhibitors Deplete Viral HPV16 Oncoproteins Through Activation of the Integrated Stress Response Pathway |
Kerry A. Smith |
9:30 AM |
Therapeutic Targeting of HPV16 E6, a Conserved Regulator of Basal Epithelial Homeostasis, for Drug Development Against Persistent Infection |
Nagayasu Egawa |
9:45 AM |
Single-cell RNA Sequencing Reveals Immunosuppressive Microenvironment in Equine Papillomavirus Type 2-Induced Genital Lesions |
Nadine Angie Werlen |
10:00 AM |
Refreshment Break |
Shannon Hall Lobby |
10:30 AM – 11:45 AM |
Oral Session 2 Continued: Virus-Host Interactions I Session Co-Chairs: Paola Blanchette & James Romero-Masters |
Shannon Hall |
10:30 AM |
Phospho-BRD4 IDR-Targeting Compounds as Anti-HPV and Anticancer Agents with Minimal Perturbation of the Cellular Transcriptome and Chromatin Landscape |
Cheng-Ming Chiang |
10:45 AM |
Analyzing the HPV16 E2 Proteome |
Claire James |
11:00 AM |
P400 Complex: Friend or Foe of Adenovirus Infection? |
Tanner M. Tessier |
11:15 AM |
Oncogenic poly (ADP-ribose) glycohydrolase (PARG) suppresses HBV cccDNA transcription via disrupting the HBx-DDB1-SMC5/6 Axis |
Cheng-Der Liu |
11:30 AM |
Cold shock during Infection Activates the MAPK Pathway Priming Kidney Cells for BK Polyomavirus Infection |
Sunnie R. Thompson |
11:45 AM – 1:30 PM |
Lunch |
Tripp Commons |
July 15 |
Tuesday Afternoon |
|
1:30 PM – 2:30 PM |
Keynote Alison McBride |
Shannon Hall |
2:30 PM |
Refreshment Break |
Shannon Hall Lobby |
3:00 PM |
Memoriams |
Shannon Hall |
4:00 PM – 6:00 PM |
Poster Session 1 Poster #s: 102-121 |
Great Hall |
6:00 PM – 7:00 PM |
Dinner |
Tripp Commons |
7:00 PM – 8:00 PM |
Oral Session 3: Viral Pathogenesis Session Co-Chairs: John Doorbar & Katerina Strati |
Shannon Hall |
7:00 PM |
Contributions of DEK Oncogene Activities to HPV-Induced Cellular Metabolism and Proliferation |
Taylor Lange |
7:15 PM |
Vocal Fold Injury is Required for MmuPV1-Induced Disease in Immunocompetent Mice |
Renee King |
7:30 PM |
Anti-Retroviral Protease Inhibitor Modulates Signaling Pathways that Potentially Promote HPV16 Infection and Carcinogenesis of Oral Epithelium |
Samina Alam |
7:45 PM |
A Subset of Oropharyngeal Cancel Cells with Low HPV mRNA is Linked to Treatment Failure Risk |
Devraj Basu |
8:00 PM |
Forming an Antiviral Alliance: Drug Combinations that Disrupt Human Adenovirus Replication |
Mackenzie Dodge |
8:10 PM |
Refreshment Break |
Shannon Hall Lobby |
8:30 PM – 9:30 PM |
Oral Session 3 Continued: Viral Pathogenesis Session Co-Chairs: John Doorbar & Katerina Strati |
Shannon Hall |
8:30 PM |
Role of Reserve Cells in the Development of HPV-Associated Neoplasia at the Cervical Transformation Zone |
John Doorbar |
8:45 PM |
MmuPV1 E7 – What do you do successfully? |
James Romero-Masters |
9:00 PM |
Understanding the Role of Highly Active Anti-Retroviral Therapy (HAART) in the Progression of HPV-Associated Oral Cancer |
Jesus Avila |
9:15 PM |
Potential sumoylation sites of JC virus ORF4 protein, Lys108 and Lys164, and their involvement in PML-NB targeting and their reorganization |
Mahmut Safak |
July 16 |
Wednesday Morning |
|
7:30 AM – 5:00 PM |
Registration |
Annex Room |
8:30 AM |
Oral Session 4: Viral Transformation/Carcinogenesis 1 Session Co-Chairs: Masa Shuda & Sunnie Thompson |
Shannon Hall |
8:30 AM |
Mouse Models of HPV-Associated Penile and Vulvar Cancer |
Sanghyuk Chung |
8:45 AM |
RB1 Inactivation and PTPN14 Inactivation are Independent Activities of HPV E7 Proteins that are Both Required for Keratinocyte Immortalization |
Pushkal Sinduvadi Ramesh |
9:00 AM |
Cancer-Associated PCNA Inhibition is Specifically Cytotoxic to Cervical Cancers |
Nick Wallace |
9:15 AM |
Human Papilloma Virus (HPV) Induced Metabolic Reprogramming in Fanconi Anemia-Deficient Head and Neck Squamous Cell Carcinoma |
Bianca Ruffolo |
9:30 AM |
A MARCHF8-Autophagy Axis for MHC-I Degradation in HPV-Positive Head and Neck Cancer |
Lexi Vu |
9:45 AM |
Refreshment Break |
Shannon Hall Lobby |
10:15 AM – 11:30 AM |
Oral Session 4 Continued: Viral Transformation/Carcinogenesis 1 Session Co-Chairs: Masa Shuda & Sunnie Thompson |
Shannon Hall |
10:15 AM |
PRMT5-Dependent SRSF1 Methylation Safeguards Tip60-EP400 Splicing in Merkel Cell Polyomavirus-Driven Merkel Cell Carcinoma |
Jingwei Cheng |
10:30 AM |
Investigating the Role of MCPyV T Antigens in Skin Cell Neuroendocrine Reprogramming during Merkel Cell Carcinoma Development |
Tejas Sabu |
10:45 AM |
A Degradable Form of Polyoma Small T Antigen Reveals the High Specificity of TAZ in Regulating Gene Expression |
Yubao Wang |
11:00 AM |
Merkel ST, PP2A And MYCL Engages with TIP60 Complex in Merkel Cell Carcinoma |
James DeCaprio |
11:15 AM |
Characterizing the Role of Somatostatin Receptor 5 in Cervical Cancer |
Rosa Cassidy |
11:30 AM |
Detection and Characterization of HPV RNA in Exosomes from Squamous Cell Carcinoma |
Eleanor Dowell |
11:45 AM |
Differential Regulation of PTPN14 in Human and Mouse Keratinocytes |
Leah Graham |
12:00 PM – 1:30 PM |
Lunch |
Tripp Commons |
July 16 |
Wednesday Afternoon |
|
1:30 PM – 2:30 PM |
Oral Session 5: Viral Infection/Life Cycle Session Co-Chairs: Jim Pipas & Katarzyna Zwolinska |
Shannon Hall |
1:30 PM |
Stress and Cell Cycle Entry Govern BKV Large T Antigen Levels and the Latent-to-Productive Infection Switch |
James Pipas |
1:45 PM |
Complement Receptor 1 and Notch 2 are Surface Mediators of Kaposi’s Sarcoma-Associated Herpesvirus Infection in Human B Cells |
Beniah Brumbaugh |
2:00 PM |
Disruption of the FA Pathway Promotes Productive HPV Infection and a State of Premalignancy |
Tafadzwa Chihanga |
2:15 PM |
High-Risk HPVs Repress m6A-RNA Modification in a Differentiation-Dependent Manner to Regulate Viral Pathogenesis |
Conor Templeton |
2:25 PM |
U4 Footprint Identified on HPV16 by Atomic Resolution CryoEM |
Ebere P. Orji |
2:35 PM |
Refreshment Break |
Shannon Hall Lobby |
3:00 PM – 4:30 PM |
Oral Session 5 Continued: Viral Infection/Life Cycle Session Co-Chairs: Jim Pipas & Katarzyna Zwolinska |
Shannon Hall |
3:00 PM |
The Rab5 Effector Rabankyrin-5 Modulates Viral Endosomal Fusion During Entry of Human Papillomavirus |
Pengwei Zhang |
3:15 PM |
Atomic Resolution Structure of Human Papillomavirus Bound to Heparin |
Caroline H. Langley |
3:30 PM |
Shedding Dynamics of Murine Polyomavirus during Acute and Long-Term Persistent Infection |
Christopher Sullivan |
3:45 PM |
Molecular Architecture of Mouse Papillomavirus E1^E4 Filaments |
Vladimir Majerciak |
4:00 PM |
Cell Surface RNAs and RNA-Binding Proteins Mediate Human Papillomavirus Cell Entry |
Jian Xie |
4:10 PM |
Phospholipase C Isoforms β4 and δ4 Aid HPV16 Genome Release |
Timothy Keiffer |
4:20 PM |
Investigating Merkel Cell Polyomavirus (MCPyV) Trafficking Mechanisms |
Isabel Amaya |
4:30 PM – 6:00 PM |
Free Time |
|
6:00 PM – 7:30 PM |
Dinner |
Tripp Commons |
July 17 |
Thursday Morning |
|
7:30 AM – 5:00 PM |
Registration |
Annex Room |
8:30 AM – 10:00 AM |
Oral Session 6: Viral-Host Interactions 2 Session Co-Chairs: Michelle Ozbun & Elizabeth White |
Shannon Hall |
8:30 AM |
Interaction of Adenovirus Type 5 E4orf4 with the PRL-CNNM Complex Enhances Magnesium Transport and Viral Replication |
Paola Blanchette |
8:45 AM |
Structural Modeling and Cryo-Electron Microscopy of Complement C4b Interactions with Adenovirus |
Nicole Wagner |
9:00 AM |
Investigation of the Relationship between Neotelomeres and Merkel Cell Polyomavirus Integration |
Gabriel Starrett |
9:15 AM |
APOBEC3B Promotes Papillomavirus Replication and Tumorigenesis in vivo |
Xingyu Liu |
9:30 AM |
Adeno-Associated Virus 2 (AAV2) – Induced RPA Exhaustion Generates Cellular DNA Damage and Restricts Viral Gene Expression |
Monnette Summers-Villarreal |
9:40 AM |
HPV16 and Tonsillar Epithelial Subsite-Specific Differences in 3D Organotypic Rafts |
Robert Jackson |
9:50 AM |
Identifying Cellular Gene Dependencies Targeted by EBV miRNAs in EBV-Positive Burkitt Lymphoma |
Isabella Castellano-Moen |
10:00 AM |
Refreshment Break |
Shannon Hall Lobby |
10:30 AM – 12:00 PM |
Oral Session 6 Continued: Viral-Host Interactions 2 Session Co-Chairs: Michelle Ozbun & Elizabeth White |
Shannon Hall |
10:30 AM |
Fibroblast-Mediated Regulation of Viral-Host Transcriptional Signatures and HPV Episome Maintenance |
Molly Bristol |
10:45 AM |
A Potential Role for Innate Immune Cells in MEK Inhibitor-Induced Tumor Regression Using a Preclinical Model of Human Papillomavirus Precancer |
Garrett Carrasco |
11:00 AM |
The Kinase Connection: E1A Exploits CDK7 and CDK9 to Promote Viral Transcription |
Katelyn M. MacNeil |
11:15 AM |
The Long Noncoding RNA Inc-FANCI-2 Inhibits RAS Signaling but Facilitates Interferon Responses in HPV16-Positive Cervical Cancer Cells |
Lulu Yu |
11:30 AM |
IRF6 Controls Epstein-Barr Virus (EBV) Lytic Reactivation and Differentiation in EBV-Infected Epithelial Cells |
Deo Singh |
11:45 AM |
KLF4-PARP1 Interaction Regulates AAV Genome Localization and Gene Expression |
Rhiannon Abrahams |
12:00 PM – 1:30 PM |
Lunch |
Tripp Commons |
July 17 |
Thursday Afternoon |
|
1:30 PM – 2:30 PM |
Oral Session 7: Virus Discovery/Biology/Transcription Session Co-Chairs: Gabe Starrett & Alix Warburton |
Shannon Hall |
1:30 PM |
E2F/NF-κB signaling controls Merkel cell polyomavirus early gene expression and the switch between viral replication and latency |
Nick Salisbury |
1:45 PM |
Leveraging the Single-Cell Transcriptome of Novel HPV-Reprogrammed Cycling Populations for Antivirals and Cancer Prevention |
Cosette Rivera-Cruz |
2:00 PM |
Unique Vulnerability of Adenovirus RNA Processing to Splicing Inhibition |
Alexander Price |
2:15 PM |
CTCF Regulates AAV and Recombinant AAV Lifecycle Through Changes in the Viral Chromatin Landscape |
Clairine Larsen |
2:30 PM |
Refreshment Break |
Shannon Hall Lobby |
3:00 PM – 4:15 PM |
Oral Session 7 Continued: Virus Discovery/Biology/Transcription Session Co-Chairs: Gabe Starrett & Alix Warburton |
Shannon Hall |
3:00 PM |
A Single m6A Motif in HPV16 Coordinates Circular (circE7) and E6*I Expression, Viral Replication, and Keratinocyte Immortalization |
Richard Wang |
3:15 PM |
Comprehensive Mapping of Episomal and Integrated Hepatitis B Genomes Uncovers Heterogeneous Transcripts and Drug-Resistant Lineages |
James M. Harris |
3:30 PM |
Identification of Disease-Associated Polyomaviruses from Cynomolgus Macaques Undergoing Stem Cell Transplantation |
Helena Vogel |
3:45 PM |
Hepatitis B Virus Localizes to Cellular Fragile Sites to Induce Replication Stress Signals and Exacerbate Cellular DNA Damage |
Gavin Marcoe |
4:00 PM |
Global Transcriptomic Analysis Identifies a Proton Therapy-Specific Response in Patient-Derived HPV-Positive Oral Cancer Organoids |
Anna Kirstein |
4:15 PM – 6:00 PM |
Poster Session 2 Poster #s: 122-138 |
Great Hall |
6:00 PM – 7:30 PM |
Dinner |
Tripp Commons |
July 18 |
Friday Morning |
|
7:30 AM – 5:00 PM |
Registration
|
Annex Room |
8:30 AM – 10:00 AM |
Oral Session 8: Viral Replication Session Co-Chairs: Chelsey Spriggs & Nick Wallace |
Shannon Hall |
8:30 AM |
Differentiation-Independent Activation of HPV Genome Replication by the IncRNA DINO |
Warda Arman |
8:45 AM |
Single-Cell RNA Sequencing Analysis Reveals Differential Gene Expression Profiles in HPV-Positive Cells Undergoing Genome Amplification |
Arushi Vats |
9:00 AM |
Topoisomerase IIα orchestrates secretion of IL-6 and IL-8 with human papillomavirus replication |
Shiyuan Hong |
9:15 AM |
Proteomics Analyses of PyV Large T-Antigen Lead to New Insights into Large T-Antigen Functions in Viral Transcription and Genome Replication |
Thomas Melendy |
9:30 AM |
Casein Kinase 1 Alpha as a Cellular Regulator in Merkel Cell Polyomavirus Persistence |
Hyun Jin Kwun |
9:40 AM |
A Genetic System to Select Mutant HPV Capsids Based on their Phenotype |
Sydney Hirsch |
9:50 AM |
Merkel Cell Polymavirus 57kt Antigen Hetero-Oligomerizes with LT and Attenuates LT-Mediated Viral DNA Replication |
Xiaochen Li |
10:00 AM |
Refreshment Break |
Shannon Hall Lobby |
10:30 AM – 12:15 PM |
Oral Session 8 Continued: Viral Replication Session Co-Chairs: Chelsey Spriggs & Nick Wallace |
Shannon Hall |
10:30 AM |
Human Papillomavirus Genomes Associate with Active Host Chromatin during Persistent Viral Infection |
Alix Warburton |
10:45 AM |
Merkel Cell Polyomavirus Small T Antigen Recruits HSP70 to Remodel Large T Complex on Origin DNA |
Li Wan |
11:00 AM |
High-Fidelity Polymerase Alpha and Error-Prone Polymerases Eta and Zeta are Required for the HPV Lifecycle and HPV Positive Cellular Fitness |
Kavi Mehta |
11:15 AM |
A Novel Metal Chelating Agent, MET-103, Inhibits HPV18 DNA Amplification and Induces Cytotoxicity in Productive HPV18 Raft Cultures with a Favorable Window of Selectivity Compared to Uninfected PHK Rafts |
N. Sanjib Banerjee |
11:30 AM |
Inhibition of PKM2 Suppresses Hepatitis B Virus Replication by Promoting the Phosphorylation-Dependent Viral Polymerase Degradation |
Ning Sun |
11:45 AM |
Does SV40 Chromatin Structure During Replication Contribute to Fate Determination |
Michaela Lano |
11:55 AM |
Topical Alisertib and Barasertib Inhibit HPV-18 DNA Amplification in Raft Cultures |
Saroj Kumar Shrestha |
12:05 PM |
Sublethal Doses of Genotoxic Immune-Conditioning Drugs, Antivirals, and Chemotherapeutics Promote BK-Polyomavirus-Induced Hemorrhagic Cystitis |
Subhajit Chatterjee |
12:15 PM – 1:30 PM |
Lunch |
Tripp Commons |
July 18 |
Friday Afternoon |
|
1:30 PM – 2:30 PM |
Oral Session 9: Viral Transformation/Carcinogenesis 2 Session Co-Chairs: Hyun Jin Kwun & Susa Wells |
Shannon Hall |
1:30 PM |
Elucidating the Role of Wnt Signaling in Merkel Cell Carcinoma |
Megha Padi |
1:45 PM |
Reversion of Merkel Cell Carcinoma to Differentiated Neuronal Cells Using CBP/p300 Inhibitors |
Joseph Collura |
2:00 PM |
Defining the Role of Epstein-Barr Virus (EBV) in Diffuse Large B-Cell Lymphoma (DLBCL) Pathogenesis |
Quincy Rosemarie |
2:15 PM |
The Etiology and Implications of Discordant Assay Results for HPV vs. p16 IHC in Oropharyngeal Cancer |
Dominick Rich |
2:30 PM |
Contributions of Small DNA Tumor Viruses to Oncoprotein-Induced Replication Stress |
Christopher D. Collins |
2:40 PM |
Refreshment Break |
Shannon Hall Lobby |
3:00 PM – 4:15 PM |
Oral Session 9 Continued: Viral Transformation/Carcinogeneis 2 Session Co-Chairs: Hyun Jin Kwun & Susa Wells |
Shannon Hall |
3:00 PM |
Assessing the Role of Methyl-CpG Binding Domain Protein 2 in HPV+ and HPV- Head and Neck Cancers |
Katerina Strati |
3:15 PM |
HPV-Inducted MARCHF8 Promotes Immune Evasion of Head and Neck Cancer by MHC-I Degradation |
Mohamed Khalil |
3:30 PM |
Distinguishing LMP2A from BCR Isotype Associated Effects in Epstein-Barr Virus Transformed Cells |
Mariah Riel |
3:45 PM |
Dysregulation of Non-AUG Translation Initiation May Promote Invasive Phenotypes in Cervical Cancer |
Grant Brooke |
4:00 PM |
Mouse Papillomavirus-Induced Rapid-Onset Squamous Cell Carcinoma: Preventative Treatment, Spontaneous Regression, and Viral Persistence |
Andrea Bilger |
5:00 PM – 7:00 PM |
Banquet Dinner |
Great Hall |
7:00 PM – 9:00 PM |
Dancing |
Tripp Commons |