*Tentative schedule – subject to change*
Thursday, June 20
| 4:30 PM | Opening Social | Tripp Commons |
| 6:00 PM | Introductory Remarks | Shannon Hall |
| 6:10 PM | Keynote: Lysosomal Signaling Regulates Longevity across the Scale | Meng Wang
HHMI Janelia Research Campus |
| 6:45 PM | Session #1: The Sidney Brenner and H. Robert Horvitz Session
Session Chairs: Caroline Kumsta and Ye Tian |
|
| 6:45 PM | Cold Temperature Delays Aging and Proteostasis Collapse | David Vilchez
CECAD-University of Cologne |
| 7:00 PM | Vitamin B12 Rescues DGLA-Induced Ferroptosis | Michael Mortensen
Jennifer Watts Lab Washington State University |
| 7:15 PM | Serotonin Deficiency from Constitutive SKN-1 Activation Drives Pathogen Apathy | Tripti Nair
Sean Curran Lab University of Southern California |
| 7:30 PM | Refreshment Break | Shannon Hall Lobby |
| 8:00 PM | A Shared Mechanism by Which Hypoxia and Intra-Complex Genetic Suppressors Rescue Mitochondrial Complex I Mutants | Joshua Meisel
Brandeis University |
| 8:15 PM | The Role of Lipid Homeostasis in Mitochondrial Surveillance and Innate Immunity | Lois Armendariz
Natasha Kirienko Lab Rice University |
| 8:30 PM | A Cell Non-Autonomous Pathway Drives Metabolism and the Mitochondrial UPR Promoting Host Resistance during Infection | Yiting Xu
Mark Pellegrino Lab University of Texas at Arlington |
| 8:45 PM | Metabolic Regulation of Feeding Behaviors | Keith Blackwell
Joslin Diabetes Center and Harvard Medical School |
Friday, June 21
| 8:00 AM | Coffee/Tea | Shannon Hall Lobby |
| 8:30 AM | Session #2: The Jennifer Doudna and Emmanuelle Charpentier Session
Session Chairs: Ashley Frakes and Robert Luallen |
Shannon Hall
|
| 8:30 AM | C. elegans Response to Infection by the Orsay Virus and Microsporidia | Emily Troemel
University of California, San Diego |
| 8:55 AM | Activation of C. elegans intestinal immunity by pathogen effector-triggered aggregation of the guard protein TIR-1 on lysosome-related organelles | Samantha Tse
Read Pukkila-Worley Lab University of Massachusetts Chan Medical School |
| 9:10 AM | CDC-48 Influences the SKN-1 Activity in Response to Pathogen Infection | Carolaing Gabaldon
Danielle Garsin Lab UTHealth Medical School |
| 9:25 AM | Endogenous Mitochondrial NAD(P)H Fluorescence Predicts Lifespan | Chris Morrow
Will Mair Lab Harvard T.H. Chang SPH |
| 9:40 AM | Post-Transcriptional Induction of Fatty Acid Biosynthesis Enables Biguanide-Mediated Lifespan Extension in Caenorhabditis elegans | Fasih Ahsan
Alex Soukas Lab Massachusetts General Hospital |
| 9:55 AM | Refreshment Break | Shannon Hall Lobby |
| 10:30 AM | Chromodomain Containing Proteins CEC-3 and CEC-6 Restrict Transgenerational Epigenetic Inheritance under Heat Stress Conditions | Phoebe Bhagoutie
Arneet Saltzman Lab University of Toronto |
| 10:45 AM | Proximity Labeling Identifies New Germ Granule and Germline Small RNA Factors in C. elegans | Sebastian Fuentes
Julie Claycomb Lab University of Toronto |
| 11:00 AM | C. elegans Hyper-Variable Regions Likely Underlie Species-Wide Adaptation to Pathogens and Other Environmental Stresses | Nicolas Moya
Erik Anderson Lab Johns Hopkins University |
| 11:15 AM | Modular Small Molecules Play a Central Role in C. elegans Physiology | Arnaud Tauffenberger
Frank Schroeder Lab Boyce Thompson Institute |
| 11:30 AM | A TFEB-TGFβ Axis Systemically Regulates Diapause, Stem Cell Longevity and Protects Against Senescence | Adam Antebi
Max Planck Institute for Biology of Ageing |
| 12:00 PM | Lunch | Tripp Commons |
| 2:00 PM | Session #3: The Martin Chalfie Session
Session Chairs: Heather Hundley and Josh Meisel |
Shannon Hall |
| 2:00 PM | Life, Death, Disease, and Motherhood: How C. elegans Survives and Protects its Young | Coleen Murphy
Princeton University |
| 2:25 PM | Systems-Level Worm Perturb-Seq Reveals Landscapes of Metabolic Rewiring and Wiring | Hefei Zhang
Marian Walhout Lab University of Massachusetts Chan Medical School |
| 2:40 PM | Characterizing the Biogenesis of Sexually Dimorphic piRNAs in C. elegans | Victoria Murphy
John Kim Lab Johns Hopkins University |
| 2:55 PM | The Dopaminergic Stress Response: Ensuring Viability at the Cost of Neurotransmission | Kielen Zuubier
Peter Douglas Lab University of Texas Southwestern Medical Center |
| 3:10 PM | Refreshment Break | Shannon Hall Lobby |
| 3:45 PM | Individual Variation of Host Immunity | Jonathan Lalsiamthara
Alejandro Aballay Lab MD Anderson |
| 4:10 PM | Proteolysis of Fatty Acid Synthase Signals Pan-Stress Resolution | Ben Weaver
UT Southwestern Medical Center |
| 4:25 PM | Conserved RNA Helicase A Facilitates Small RNA Biogenesis and Preserves Germline Fertility | Olivia Gaylord
Heng-Chi Lee Lab University of Chicago |
| 4:40 PM | A fat-2 Suppressor Screen Reveals Genetic Adaptations to Polyunsaturated Fatty Acid Deficiency | Delaney Kaper
Marc Pilon Lab University of Gothenburg |
| 5:00 PM | Lightening Talks | Shannon Hall |
| 5:30 PM | Dinner | Tripp Commons |
| 7:30 PM | Poster Session A – Even Numbers | Great Hall |
Saturday, June 22
| 8:00 AM | Coffee/Tea | Shannon Hall Lobby |
| 8:30 AM | Session #4: The Carolyn Bertozzi Session
Session Chair: Jennifer Powell and Wen Tang |
Shannon Hall |
| 8:30 AM | Regulation of Autophagy in Aging and Disease | Malene Hansen
The Buck Institute |
| 8:55 AM | Eukaryotic Elongation Factor 2 Kinase EFK-1/eEF2K Promotes Starvation Resistance by Preventing Oxidative Damage in C. elegans | Junran Yan
Stefan Taubert Lab University of British Columbia |
| 9:10 AM | The TWK-26 Potassium Channel Governs Nutrient Absorption in the C. elegans Intestine | Sarah Torzone
Robert Dowen Lab The University of North Carolina at Chapel Hill |
| 9:25 AM | Identifying the Aging Intestine Secretome and its Role in Lifespan Regulation | Jason Miklas
Anne Brunet Lab Stanford University |
| 9:40 AM |
Exploring the Regulation and Function of an Ancient microRNA Family in C. elegans
|
Kasuen Kotagama
Katherine McJunkin Lab National Institutes of Health |
| 9:55 AM | Refreshment Break | Shannon Hall Lobby |
| 10:30 AM | Chemical and Elemental Imaging of Caenorhabditis elegans with MALDI and LA-ICP Mass Spectrometry | Tian (Autumn) Qiu
Michigan State University |
| 10:45 AM | DNA Damage Induced Acetyl-CoA Dynamics in Aging | Aditi Gurkar
University of Pittsburgh |
| 11:00 AM | Dual Transcriptional Programs Coordinate Lipogenic and UPRGolgi Programs in C. elegans and Human Cells | Amy Walker
University of Massachusetts Chan Medical School |
| 11:15 AM | siRNA Handoff During RNAi | Tai Montgomery
Colorado State University |
| 11:30 AM | A Frameshift Between Overlapping ORFs of the ZIP-2 Transcription Factor Detects and Defends Translational Elongation Defects | Gary Ruvkun
Massachusetts General Hospital and Harvard Medical School |
| 12:00 PM | Lunch | Tripp Commons |
| 2:00 PM | Session #5: The Craig Mello and Andrew Fire Session
Session Chairs: Arneet Saltzman and Ryo Sanabria |
Shannon Hall |
| 2:00 PM | Roles for Small RNAs in Stress and Fertility | Amy Pasquinelli
University of California, San Diego |
| 2:25 PM | Compartmentalization of Small RNA Pathways Contributes to Binding Specificity for Nuclear Argonaute Proteins | Shihui Chen
Carolyn Phillips Lab University of Southern California |
| 2:40 PM | Stress-activated KGB-1/JNK MAPK and Altered Competition Enables Microbiome Remodeling Providing Protection from Environmental Toxins | Sarah El Khoury
Michael Shapira Lab University of California, Berkeley |
| 2:55 PM | Investigating Mechanisms of Microsporidia Host Cell Invasion and Specificity in Nematodes | Jonathan Tersigni
Aaron Reinke Lab University of Toronto |
| 3:10 PM | Refreshment Break | Shannon Hall Lobby |
| 3:45 PM | Regulation of an Extracellular Unfolded Protein Response | Cole Haynes
University of Massachusetts Chan Medical School |
| 4:10 PM | Stress-Driven Microbial Evolution to Improve Host Health and Longevity | Ajay Bhat
Scott Leiser Lab University of Michigan |
| 4:25 PM | An Ancient System that Excises Transposons from Host mRNAs | Scott Kennedy
Harvard Medical School |
| 4:40 PM | Gametogenesis Mutants Reveal Molecular Links between Reproduction, Fat Metabolism, and Longevity in C. elegans | Amaresh Chaturbedi
Sylvia Lee Lab Cornell University |
| 5:00 PM | Lightening Talks | Shannon Hall |
| 5:30 PM | Dinner | Tripp Commons |
| 7:30 PM | Poster Session B – Odd Numbers | Great Hall |
| 9:00 PM | Dance | Tripp Commons |
Sunday, June 23
| 8:00 AM | Coffee/Tea | Shannon Hall Lobby |
| 8:30 AM | Session #6: The Katelyn Karikó Session
Session Chair: Claire Richardson and Robert Dowen |
Shannon Hall |
| 8:30 AM | Microbial Modulation of Neuron-Specific DAF-7 Expression and Behavioral State | Dennis Kim
Harvard University |
| 8:55 AM | DAF-18/PTEN Protein-Phosphatase Activity Promotes Starvation Resistance During L1 arrest | Jingxian Chen
Ryan Baugh Lab Duke University |
| 9:10 AM | G Protein-Coupled Receptor NMUR-1 Regulates Enery Homeostasis and ROS Production in Response to Pathogen Infections | Phillip Wibisono
Jingru Sun Lab Washington State University |
| 9:25 AM | On the Influence of the Nervous System on Lipid Metabolism and Longevity | Supriya Srinivasan
The Scripps Research Institute |
| 9:40 AM | N-glycosylation of SKN-1/Nrf Fine-Tunes Stress Responses | Nic Lehrbach
Fred Hutchinson Cancer Center |
| 9:55 AM | Refreshment Break | Shannon Hall Lobby |
| 10:30 AM | Neuronal Control of Mitochondrial Stress Response: Implications for Aging and Health | Ye Tian
Institute of Genetics and Developmental Biology, Chinese Academy of Sciences |
| 10:45 AM | In Search of the ER Guardian of Oxygen Galaxy: How Worm(holes) and AI Can Help | Dengke Ma
University of California, San Franscisco |
| 10:55 AM | Neuronal ILC-17.1 Controls the C. elegans dauer Pathway Through CEP-1: Ancestral Roles for IL-17 and p53? | Veena Prahlad
Roswell Park Comprehensive Cancer Center |
| 11:10 AM | HLH-30/TFEB-Mediated Control of the Host Response | Javier Irazoqui
University of Massachusetts Chan Medical School |
| 11:25 AM | Macroautophagy Contributes to Lysosome Damage and Impaired Re-Activation of Quiescent Cells | Andrew Dillin
University of California, Berkeley |
| 11:50 AM | Concluding Remarks | Shannon Hall |
| 12:00 PM | Lunch with CE Neuro Meeting Attendees | Tripp Commons |
Keynote Speaker
Meng Wang, HHMI Janelia Research Campus
Invited Speakers
Aaron Reinke, University of Toronto
Adam Antebi, Max Planck Institute
Aditi Gurkar, University of Pittsburg
Alejandro Aballay, Oregon Health & Science University
Alex Soukas, Massachusetts General Hospital and Harvard Medical School
Amy Pasquinelli, University of California, San Diego
Amy Walker, University of Massachusetts Chan Medical School
Andrew Dillin, University of California, Berkeley
Anne Brunet, Stanford University
Arjumaund Ghazi, UPMC Children’s Hospital of Pittsburgh
Ben Weaver, UT Southwestern Medical Center
Cole Haynes, University of Massachusetts Chan Medical School
Coleen Murphy, Princeton University
Danielle Garsin, University of Texas Health Science Center
David Vilchez, University of Cologne, Germany
Denke Ma, University of California, San Francisco
Dennis Kim, Boston Children’s Hospital
Emily Troemel, University of California, San Diego
Erik Anderson, Northwestern University
Frank Schroeder, Cornell University
Gary Ruvkun, Massachusetts General Hospital and Harvard Medical School
Heng-Chi Lee, University of Chicago
Javier Irazoqui, University of Massachusetts Chan Medical School
Jennifer Watts, Washington State University
Jingru Sun, Washington State University
Julie Claycomb, University of Toronto
Katherine McJunkin, National Institute of Health
Keith Blackwell, Joslin Diabetes Center and Harvard Medical School
Liu Ying, Peking University
Malene Hansen, The Buck Institute
Marc Pilon, University of Gothenburg
Marian Walhout, University of Massachusetts Chan Medical School
Mark Pellegrino, University of Texas, Arlington
Natasha Kirienko, Rice University
Nicolas Lehrbach, Fred Hutchinson Cancer Center
Ryan Baugh, Duke University
Scott Leiser, University of Michigan
Sean Curran, University of Southern California
Stephen Taubert, University of British Columbia
Supriya Srinivasan, The Scripps Research Institute
Sylvia Lee, Cornell University
Tai Montgomery, Colorado State University
Veena Prahlad, Roswell Park Comprehensive Cancer Center
Will Mair, Harvard TH Chan School of Public Health